Human Lysyl tRNA synthetase (KARS) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KARS1
Locus ID	3735
Kit Components	GA102512G1, Lysyl tRNA synthetase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102512G2, Lysyl tRNA synthetase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102512G3, Lysyl tRNA synthetase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001130089, NM_005548
Synonyms	CMTRIB; DFNB89; KARS1; KARS2; KRS
Summary	Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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