Human Kir2.1 (KCNJ2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KCNJ2
Locus ID	3759
Kit Components	GA102535G1, Kir2.1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102535G2, Kir2.1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102535G3, Kir2.1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000891
Synonyms	ATFB9; HHBIRK1; HHIRK1; IRK1; KIR2.1; LQT7; SQT3
Summary	Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008]

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