Human Leucyl cystinyl aminopeptidase (LNPEP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LNPEP
Locus ID	4012
Kit Components	GA102719G1, Leucyl cystinyl aminopeptidase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102719G2, Leucyl cystinyl aminopeptidase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102719G3, Leucyl cystinyl aminopeptidase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005575, NM_175920
Synonyms	CAP; IRAP; P-LAP; PLAP
Summary	This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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