Human MAGEA6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAGEA6
Locus ID	4105
Kit Components	GA102790G1, MAGEA6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102790G2, MAGEA6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102790G3, MAGEA6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005363, NM_175868
Synonyms	CT1.6; MAGE-3b; MAGE3B; MAGE6
Summary	This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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