Human MDH2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MDH2
Locus ID	4191
Kit Components	GA102856G1, MDH2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102856G2, MDH2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102856G3, MDH2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001282403, NM_001282404, NM_005918, NR_104165
Synonyms	M-MDH; MDH; MGC:3559; MOR1
Summary	Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

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