Human MITF activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MITF
Locus ID	4286
Kit Components	GA102913G1, MITF gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102913G2, MITF gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102913G3, MITF gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000248, NM_001184967, NM_001184968, NM_006722, NM_198158, NM_198159, NM_198177, NM_198178, NM_001354604, NM_001354605, NM_001354606, NM_001354607, NM_001354608
Synonyms	bHLHe32; CMM8; MI; WS2; WS2A
Summary	The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]

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