Human MOCS1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MOCS1
Locus ID	4337
Kit Components	GA102954G1, MOCS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102954G2, MOCS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102954G3, MOCS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001075098, NM_005942, NM_005943, NM_138928, NR_033233, NM_001358529, NM_001358530, NM_001358531, NM_001358533, NM_001358534
Synonyms	MIG11; MOCOD; MOCODA
Summary	Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16. [provided by RefSeq, Nov 2017]

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