Human Melatonin Receptor 1B (MTNR1B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MTNR1B
Locus ID	4544
Kit Components	GA103027G1, Melatonin Receptor 1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103027G2, Melatonin Receptor 1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103027G3, Melatonin Receptor 1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005959
Synonyms	FGQTL2; MEL-1B-R; MT2
Summary	This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]

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