Human MTR activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MTR
Locus ID	4548
Kit Components	GA103029G1, MTR gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103029G2, MTR gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103029G3, MTR gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000254, NM_001291939, NM_001291940
Synonyms	cblG; HMAG; MS
Summary	This gene encodes the 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

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