Human MX1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MX1
Locus ID	4599
Kit Components	GA103045G1, MX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103045G2, MX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103045G3, MX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001144925, NM_001178046, NM_001282920, NM_002462
Synonyms	IFI-78K; IFI78; MX; MxA
Summary	This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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