Human MYO6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MYO6
Locus ID	4646
Kit Components	GA103085G1, MYO6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103085G2, MYO6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103085G3, MYO6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001300899, NM_004999, NM_001368138, NM_001368140, NM_001368866, NR_160539, NM_001368136, NM_001368137, NM_001368139, NM_001368865, NR_160538
Synonyms	DFNA22; DFNB37
Summary	This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

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