Human Myocilin (MYOC) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MYOC
Locus ID	4653
Kit Components	GA103091G1, Myocilin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103091G2, Myocilin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103091G3, Myocilin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000261
Synonyms	GLC1A; GPOA; JOAG; JOAG1; myocilin; TIGR
Summary	MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq, Jul 2008]

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