Human NCF2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NCF2
Locus ID	4688
Kit Components	GA103118G1, NCF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103118G2, NCF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103118G3, NCF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000433, NM_001127651, NM_001190789, NM_001190794
Synonyms	NCF-2; NOXA2; P67-PHOX; P67PHOX
Summary	This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]

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