Human IKB beta (NFKBIB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NFKBIB
Locus ID	4793
Kit Components	GA103195G1, IKB beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103195G2, IKB beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103195G3, IKB beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001001716, NM_001243116, NM_002503, NR_040515, NM_001369699, NM_001369700, NR_161470
Synonyms	IKBB; TRIP9
Summary	The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]

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