Human IKB epsilon (NFKBIE) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NFKBIE
Locus ID	4794
Kit Components	GA103196G1, IKB epsilon gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103196G2, IKB epsilon gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103196G3, IKB epsilon gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004556
Synonyms	IKBE
Summary	The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. [provided by RefSeq, Sep 2011]

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