Human OXCT1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	OXCT1
Locus ID	5019
Kit Components	GA103349G1, OXCT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103349G2, OXCT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103349G3, OXCT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000436, NM_001364299, NM_001364303, NM_001364300, NM_001364301, NM_001364302, NR_157114
Synonyms	OXCT; SCOT
Summary	This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq, Jul 2008]

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