Human PFKL activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PFKL
Locus ID	5211
Kit Components	GA103501G1, PFKL gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103501G2, PFKL gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103501G3, PFKL gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001002021, NM_002626, NR_024108
Synonyms	ATP-PFK; PFK-B; PFK-L
Summary	This gene encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis). This enzyme is a tetramer that may be composed of different subunits encoded by distinct genes in different tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

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