Human Prohibitin (PHB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PHB
Locus ID	5245
Kit Components	GA103523G1, Prohibitin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103523G2, Prohibitin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103523G3, Prohibitin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001281496, NM_001281497, NM_001281715, NM_002634
Synonyms	HEL-215; HEL-S-54e; PHB1
Summary	This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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