Human Plakophilin 2 (PKP2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PKP2
Locus ID	5318
Kit Components	GA103579G1, Plakophilin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103579G2, Plakophilin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103579G3, Plakophilin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001005242, NM_004572
Synonyms	ARVD9
Summary	This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008]

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