Human Plexin B1 (PLXNB1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLXNB1
Locus ID	5364
Kit Components	GA103621G1, Plexin B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103621G2, Plexin B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103621G3, Plexin B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001130082, NM_002673
Synonyms	PLEXIN-B1; PLXN5; SEP
Summary	Receptor for SEMA4D (PubMed:19843518, PubMed:20877282, PubMed:21912513). Plays a role in GABAergic synapse development (By similarity). Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development (By similarity). Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton (PubMed:12196628, PubMed:15210733). Plays a role in axon guidance, invasive growth and cell migration (PubMed:12198496).[UniProtKB/Swiss-Prot Function]

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