Human CTSA activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CTSA
Locus ID	5476
Kit Components	GA103694G1, CTSA gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103694G2, CTSA gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103694G3, CTSA gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000308, NM_001127695, NM_001167594, NR_133656
Synonyms	GLB2; GSL; NGBE; PPCA; PPGB
Summary	This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis. [provided by RefSeq, Nov 2015]

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