Human Cyclophilin B (PPIB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPIB
Locus ID	5479
Kit Components	GA103696G1, Cyclophilin B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103696G2, Cyclophilin B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103696G3, Cyclophilin B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000942
Synonyms	CYP-S1; CYPB; HEL-S-39; OI9; SCYLP
Summary	The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]

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