Human Protein phosphatase inhibitor 1 (PPP1R1A) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPP1R1A
Locus ID	5502
Kit Components	GA103707G1, Protein phosphatase inhibitor 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103707G2, Protein phosphatase inhibitor 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103707G3, Protein phosphatase inhibitor 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006741
Synonyms	I1; IPP1
Summary	Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.[UniProtKB/Swiss-Prot Function]

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