Human Protamine 2 (PRM2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PRM2
Locus ID	5620
Kit Components	GA103807G1, Protamine 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103807G2, Protamine 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103807G3, Protamine 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001286356, NM_001286357, NM_001286358, NM_001286359, NM_002762, NR_104428
Synonyms	CT94.2
Summary	Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis, and are the major DNA-binding proteins in the nucleus of sperm in many vertebrates. They package the sperm DNA into a highly condensed complex in a volume less than 5% of a somatic cell nucleus. Many mammalian species have only one protamine (protamine 1); however, a few species, including human and mouse, have two. This gene encodes protamine 2, which is cleaved to give rise to a family of protamine 2 peptides. Alternatively spliced transcript variants have also been found for this gene. [provided by RefSeq, Sep 2015]

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