Human PRODH activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PRODH
Locus ID	5625
Kit Components	GA103811G1, PRODH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103811G2, PRODH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103811G3, PRODH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001195226, NM_005974, NM_016335
Synonyms	HSPOX2; PIG6; POX; PRODH1; PRODH2; TP53I6
Summary	This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

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