Human RAD21 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RAD21
Locus ID	5885
Kit Components	GA103998G1, RAD21 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103998G2, RAD21 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103998G3, RAD21 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006265
Synonyms	CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1; SCC1
Summary	The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008]

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