Human KDM5A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KDM5A
Locus ID	5927
Kit Components	GA104037G1, KDM5A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104037G2, KDM5A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104037G3, KDM5A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042603, NM_005056
Synonyms	RBBP-2; RBBP2; RBP2
Summary	This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013]

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