Human Reticulon 2 (RTN2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RTN2
Locus ID	6253
Kit Components	GA104238G1, Reticulon 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104238G2, Reticulon 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104238G3, Reticulon 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005619, NM_206900, NM_206901, NM_206902
Synonyms	NSP2; NSPL1; NSPLI; SPG12
Summary	This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Reticulon proteins also play an important role in the replication of positive-strand RNA (ssRNA) viruses. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Aug 2020]

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