Human SDHA activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SDHA
Locus ID	6389
Kit Components	GA104344G1, SDHA gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104344G2, SDHA gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104344G3, SDHA gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001294332, NM_004168, NM_001330758
Synonyms	CMD1GG; FP; PGL5; SDH1; SDH2; SDHF
Summary	This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

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