Human Semaphorin 3F (SEMA3F) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SEMA3F
Locus ID	6405
Kit Components	GA104358G1, Semaphorin 3F gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104358G2, Semaphorin 3F gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104358G3, Semaphorin 3F gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001318798, NM_001318800, NM_004186
Synonyms	SEMA-IV; SEMA4; SEMAK
Summary	This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin loop and a C-terminal basic domain. This gene is expressed by the endothelial cells where it was found to act in an autocrine fashion to induce apoptosis, inhibit cell proliferation and survival, and function as an anti-tumorigenic agent. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

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