Human SFRP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SFRP1
Locus ID	6422
Kit Components	GA104367G1, SFRP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104367G2, SFRP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104367G3, SFRP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003012
Synonyms	FRP; FRP-1; FRP1; FrzA; SARP2
Summary	This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]

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