Human SGSH activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SGSH
Locus ID	6448
Kit Components	GA104389G1, SGSH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104389G2, SGSH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104389G3, SGSH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000199, NM_001352921, NM_001352922, NR_148201
Synonyms	HSS; MPS3A; SFMD
Summary	This gene encodes the enzyme sulfamidase; one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with the lysosomal storage disease mucopolysaccaridosis IIIA, also known as Sanfilippo syndrome A, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined. [provided by RefSeq, Jun 2017]

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