Human EAAT3 (SLC1A1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SLC1A1
Locus ID	6505
Kit Components	GA104430G1, EAAT3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104430G2, EAAT3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104430G3, EAAT3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004170
Synonyms	DCBXA; EAAC1; EAAT3; SCZD18
Summary	This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010]

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