Human Noradrenaline transporter (SLC6A2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SLC6A2
Locus ID	6530
Kit Components	GA104454G1, Noradrenaline transporter gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104454G2, Noradrenaline transporter gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104454G3, Noradrenaline transporter gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001043, NM_001172501, NM_001172502, NM_001172504
Synonyms	NAT1; NET; NET1; SLC6A5
Summary	This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]

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