Human SLUG (SNAI2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SNAI2
Locus ID	6591
Kit Components	GA104507G1, SLUG gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104507G2, SLUG gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104507G3, SLUG gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003068
Synonyms	SLUG; SLUGH1; SNAIL2; WS2D
Summary	This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]

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