Human SPG7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SPG7
Locus ID	6687
Kit Components	GA104587G1, SPG7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104587G2, SPG7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104587G3, SPG7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003119, NM_199367, NM_001363850
Synonyms	CAR; CMAR; PGN; SPG5C
Summary	This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2014]

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