Human NEK4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NEK4
Locus ID	6787
Kit Components	GA104673G1, NEK4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104673G2, NEK4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104673G3, NEK4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001193533, NM_003157, NM_001348412, NM_001348413, NM_001348414
Synonyms	NRK2; pp12301; STK2
Summary	The protein encoded by this gene is a serine/threonine protein kinase required for normal entry into replicative senescence. The encoded protein also is involved in cell cycle arrest in response to double-stranded DNA damage. Finally, this protein plays a role in maintaining cilium integrity, and defects in this gene have been associated with ciliopathies. [provided by RefSeq, Jan 2017]

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