Human Munc18 1 (STXBP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	STXBP1
Locus ID	6812
Kit Components	GA104687G1, Munc18 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104687G2, Munc18 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104687G3, Munc18 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001032221, NM_003165
Synonyms	MUNC18-1; NSEC1; P67; RBSEC1; UNC18
Summary	This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]

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