Human Treacher Collins syndrome protein (TCOF1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TCOF1
Locus ID	6949
Kit Components	GA104797G1, Treacher Collins syndrome protein gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104797G2, Treacher Collins syndrome protein gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104797G3, Treacher Collins syndrome protein gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000356, NM_001008656, NM_001008657, NM_001135243, NM_001135244, NM_001135245, NM_001195141
Synonyms	MFD1; TCS; TCS1; treacle
Summary	This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

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