Human TESK1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TESK1
Locus ID	7016
Kit Components	GA104826G1, TESK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104826G2, TESK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104826G3, TESK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001318230, NM_006285
Synonyms	OTTHUMP00000021332; testis-specific kinase-1; testis-specific kinase 1; testis-specific protein kinase 1; testis specific kinase-1
Summary	This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

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