Human Topoisomerase I (TOP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TOP1
Locus ID	7150
Kit Components	GA104938G1, Topoisomerase I gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104938G2, Topoisomerase I gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104938G3, Topoisomerase I gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003286
Synonyms	TOPI
Summary	This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]

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