Human Tryptophan Hydroxylase (TPH1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TPH1
Locus ID	7166
Kit Components	GA104950G1, Tryptophan Hydroxylase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104950G2, Tryptophan Hydroxylase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104950G3, Tryptophan Hydroxylase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004179
Synonyms	TPRH; TRPH
Summary	This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009]

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