Human U2AF35 (U2AF1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	U2AF1
Locus ID	7307
Kit Components	GA105033G1, U2AF35 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105033G2, U2AF35 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105033G3, U2AF35 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001025203, NM_001025204, NM_006758
Synonyms	FP793; RN; RNU2AF1; U2AF35; U2AFBP
Summary	This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

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