Human Upstream Binding Protein 1 (UBP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UBP1
Locus ID	7342
Kit Components	GA105056G1, Upstream Binding Protein 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105056G2, Upstream Binding Protein 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105056G3, Upstream Binding Protein 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001128160, NM_001128161, NM_014517
Synonyms	LBP-1a; LBP-1B; LBP1A; LBP1B
Summary	Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.[UniProtKB/Swiss-Prot Function]

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