Human UGT (UGT2B4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UGT2B4
Locus ID	7363
Kit Components	GA105071G1, UGT gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105071G2, UGT gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105071G3, UGT gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001297615, NM_001297616, NM_021139
Synonyms	HLUG25; UDPGT2B4; UDPGTh-1; UDPGTH1; UGT2B11
Summary	UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.[UniProtKB/Swiss-Prot Function]

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