Human WEE1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	WEE1
Locus ID	7465
Kit Components	GA105143G1, WEE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105143G2, WEE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105143G3, WEE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001143976, NM_003390
Synonyms	WEE1A; WEE1hu
Summary	This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008]

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