Human CRM1 (XPO1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	XPO1
Locus ID	7514
Kit Components	GA105172G1, CRM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105172G2, CRM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105172G3, CRM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_003400
Synonyms	CRM1; emb; exp1
Summary	This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015]

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