Human GCS1 (MOGS) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MOGS
Locus ID	7841
Kit Components	GA105331G1, GCS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105331G2, GCS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105331G3, GCS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001146158, NM_006302
Synonyms	CDG2B; CWH41; DER7; GCS1
Summary	This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

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