Human FRA1 (FOSL1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FOSL1
Locus ID	8061
Kit Components	GA105397G1, FRA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105397G2, FRA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105397G3, FRA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001300844, NM_001300855, NM_001300856, NM_001300857, NM_005438, NR_125339
Synonyms	FRA; fra-1; FRA1
Summary	The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

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