Human HPS2 (AP3B1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AP3B1
Locus ID	8546
Kit Components	GA105660G1, HPS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105660G2, HPS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105660G3, HPS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001271769, NM_003664
Synonyms	ADTB3; ADTB3A; HPS; HPS2; PE
Summary	This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]

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